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Anatomy

Greater Vestibular Glands

/grey-ter ve-stib-yuh-ler gland-es/

Eponym: Bartholin's Glands

Structure

The greater vestibular glands are a pair of small, symmetrical structures, each about the size of a pea, located within the assigned female at birth pelvic region, specifically in the superficial perineal pouch at the posterior pole of the vestibular bulbs.[1] The greater vestibular glands play a significant role in reproductive and sexual health.[1] These oval-shaped glands measure approximately 0.5 cm in diameter and are connected to the posterolateral aspect of the vaginal orifice by a two-centimeter-long efferent duct.[2]

Function

The greater vestibular glands are primarily made up of glandular tissue that secretes a mucus-like fluid into the vaginal vestibule.[1] This fluid plays a crucial role in providing vaginal lubrication, which is essential for enhancing sexual arousal and ensuring comfort during intercourse.[3] Furthermore, these secretions play a vital role in maintaining a healthy vaginal environment, offering protection against infections and irritation.[4] Sometimes, the ducts of the greater vestibular glands can become blocked, leading to the formation of cysts. In some instances, these cysts can become infected and evolve into abscesses, potentially necessitating medical intervention.[2]

References
  1. Moore KL, Dalley II AF, Agur AMR. Clinically Oriented Anatomy. 8th ed. Wolters Kluwer; 2018.

  2. Quaresma C, Sparzak PB. Anatomy, Abdomen and Pelvis: Bartholin Gland. In: StatPearls. StatPearls Publishing; 2024.

  3. Lee MY, Dalpiaz A, Schwamb R, Miao Y, Waltzer W, Khan A. Clinical Pathology of Bartholin’s Glands: A Review of the Literature. Current Urology. 2015;8(1):22-25.

  4. Bartholin’s gland. Britannica. June 23, 2026.

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